Browsing by Author "Langhorne, Jean"

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B Cell Memory to 3 Plasmodium falciparum Blood-Stage Antigens in a Malaria-Endemic Area

Dorfman, Jeffrey R.; Bejon, Philip; Ndungu, Francis M.; Langhorne, Jean; Kortok, Moses Mosobo; Lowe, Brett S.; Mwangi, Tabitha; Williams, Thomas N.; Marsh, Kevin (Journal of Infectious Diseases, 2005-05)

To gain insight into why antibody responses to malarial antigens tend to be short lived, we studied antigenspecific memory B cells from donors in an area where malaria is endemic.We compared antibody and memory B cell ...
CD4 T Cell Responses to a Variant Antigen of the Malaria Parasite Plasmodium falciparum, Erythrocyte Membrane Protein–1, in Individuals Living in Malaria-Endemic Areas

Allsopp, Catherine E. M.; Sanni, Latifu A.; Reubsaet, Lieke; Ndungu, Francis; Newbold, Chris; Tabitha Mwangi,; Marsh, Kevin; Langhorne, Jean (Infectious Diseases, 2002)

Plasmodium falciparum erythrocyte membrane protein–1 (PfEMP-1) is a variant antigen on the surface of malaria-infected red blood cells. Antibody responses to PfEMP-1 correlate with immunity, and, therefore, PfEMP-1 may ...