Browsing by Author "Mackinnon, Margaret J."
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Breadth and Magnitude of Antibody Responses to Multiple Plasmodium falciparum Merozoite Antigens Are Associated with Protection from Clinical Malaria
Osier, Faith H. A.; Fegan, Gregory; Polley, Spencer D.; Murungi, Linda; Verra, Federica; Tetteh, Kevin K. A.; Lowe, Brett; Mwangi, Tabitha; Bull, Peter C.; Thomas, Alan W.; Cavanagh, David R.; McBride, Jana S.; Lanar, David E.; Mackinnon, Margaret J.; Conway, David J.; Marsh, Kevin (Infection and Immunity, 2008-02-23)Individuals living in areas where malaria is endemic are repeatedly exposed to many different malaria parasite antigens. Studies on naturally acquired antibody-mediated immunity to clinical malaria have largely focused ... -
Heritability of Malaria in Africa
Mackinnon, Margaret J.; Mwangi, Tabitha; Snow, Robert W.; Marsh, Kevin; Williams, Thomas N. (PLoS MEDICINE, 2008-11-08)Background While many individual genes have been identified that confer protection against malaria, the overall impact of host genetics on malarial risk remains unknown. Methods and Findings We have used pedigree-based ...