Browsing Department of Biochemistry and Biotechnology by Title
Now showing items 24-36 of 36
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Reduction of electron-deficient pyrroles using group I and II metals in ammonia
(RSC Publishing, 1998)The preparation and Birch reduction of a series of electron-deficient pyrroles is described. This methodology allows the synthesis of a variety of C-2 substituted 3-pyrrolines ‡ in good to excellent yields. The role of ... -
Reductivealdolreactions on aromatic heterocycles
(Elsevier, 2000-02-12)The Birch reduction of both pyrroles and furans can be quenched with an aldehyde electrophile, thus constituting a reductivealdolreaction. Although the reaction was not stereoselective, the pyrrolines derived from reduction ... -
Ring Contraction of α,β-Unsaturated Cyclic Amines with cis-Dihydroxylation at the α,β-Position
(The Japan Institute of Heterocyclic Chemistry, 2009-01)α,β-Unsaturated cyclic amines are oxidized by OsO4 to afford α,β-cis-dihydroxylated compounds which are thermodynamically transformed into ring-opened keto-alcohols. The keto-alcohols are then cyclized to form synthetically ... -
Starch hydrolysing Bacillus halodurans isolates from a Kenyan soda lake
(2004)Fourteen obligate alkaliphilic and halotolerant bacterial isolates, exhibiting extracellular amylase activity at 55degreesC and pH 10, were isolated from hot springs around Lake Bogoria, Kenya. From 16S rDNA sequence ... -
The stereoselectiveBirchreduction of pyrroles
(ELSELVIER, 1999-01-15)The Birchreduction has been applied to electron-deficient pyrroles substituted with a chiral auxiliary at the C-2 position. Using either 8-phenylmenthol ortrans-2-(α-cumyl)cyclohexanol (TCC) as auxiliaries, high levels of ... -
Surfactants from xylan: Production of n-octyl xylosides using a highly thermostable xylanase from Thermotoga neapolitana
(Elsevier, 2010)A highly thermostable recombinant xylanase from Thermotoga neapolitana was used as a catalyst for single-step synthesis of n-octyl xylobioside and n-octyl xylotrioside from xylan and n-octanol. Effect of xylan concentration, ... -
Surfactants from xylan: Production of n-octyl xylosides using a highly thermostable xylanase from Thermotoga neapolitana
(Elsevier, 2010)Full-text Full text is not available in this archive Alternative location (URL) http://dx.doi.org/10.1016/j.pr... Restricted Access (Alternative Location) Publication/Series Process Biochemistry Publishing year 2010 Volume ... -
Synthesis of 5-hydroxy-2,3,4,5-tetrahydro-[1H]-2-benzazepin-4-ones: selective antagonists of muscarinic (M3) receptors.
(PubMed, 2008-06-21)Two approaches to tetrahydro-[1H]-2-benzazepin-4-ones of interest as potentially selective, muscarinic (M(3)) receptor antagonists have been developed. Base promoted addition of 2-(tert-butoxycarbonylamino)methyl-1,3-dithiane ... -
Synthesis of a5-alkoxypyrido[4,3-d]pyrimidin-4(3H)-onederivativeviaaregioselectiveMeisenheimerN-oxiderearrangement
(Elsevier, 2004-05-03)The synthetic strategy towards a5-alkoxypyrido[4,3-d]pyrimidin-4(3H)-one is described utilizing a selective N-oxidation and subsequent regioselectiveMeisenheimerN-oxiderearrangement as key steps. -
Thermostable alkaline phytase from Bacillus sp. MD2: Effect of divalent metals on activity and stability
(Elsevier, 2011)Phytate, the major source of phosphorus in seeds, exists as a complex with different metal ions. Alkaline phytases are known to dephosphorylate phytate complexed with calcium ions in contrast to acid phytases that act only ... -
Thermostable alkaline phytase from Bacillus sp. MD2: Effect of divalent metals on activity and stability
(Elsevier, 2011-07-07)Phytate, the major source of phosphorus in seeds, exists as a complex with different metal ions. Alkaline phytases are known to dephosphorylate phytate complexed with calcium ions in contrast to acid phytases that act only ... -
Utility of the Ammonia-Free Birch Reduction of Electron-Deficient Pyrroles: Total Synthesis of the 20S Proteasome Inhibitor, clasto-Lactacystin b-Lactone
(Chem. Eur. J., 2005)A new synthesis of the 20S proteasome inhibitor clasto-lactacystin b-lactone is described. Our route to this important natural product involves the partial reduction of an electron deficient pyrrole as a key step. By ... -
Utility of the Ammonia-Free Birch Reduction of Electron-Deficient Pyrroles: Total Synthesis of the 20S Proteasome Inhibitor, clasto-Lactacystin β-Lactone
(Wiley Online Library, 2005-05-02)A new synthesis of the 20S proteasome inhibitor clasto-lactacystin β-lactone is described. Our route to this important natural product involves the partial reduction of an electron deficient pyrrole as a key step. By ...