Department of Biological Sciences
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ANALYSIS OF EXPRESSION LEVELS OF APOPTOTIC GENES IN BREAST CANCER AMONG KENYAN, AFRICAN-AMERICAN AND CAUCASIAN WOMEN
(Pwani University, 2022-12-11)Breast cancer is the most common type of cancer diagnosed in women worldwide and also one of the highest-ranking causes of cancer-related deaths. The histogenesis of breast cancer is well studied with five different molecular ... -
GENOME-WIDE ASSOCIATION STUDY OF VITAMIN D STATUS IN KENYAN CHILDREN IN KILIFI AND GAMBIAN CHILDREN IN WEST KIANG
(Pwani University, 2022-11-11)Vitamin D deficiency is a major public health issue linked to autoimmune disorders, cancer, cardiovascular and musculoskeletal diseases among other medical conditions. The link between vitamin D status and these diseases ... -
METATRANSCRIPTOMICS ANALYSIS OF CORAL MUCUS-ASSOCIATED MICROBIOME IN THE KENYAN COAST
(Pwani University, 2022-12-16)Coral reefs are significant marine ecosystems located in shallow tropical and subtropical seas that provide important services. More than 25% of all marine species depend on coral reefs as breeding and feeding sites, as ... -
DEVELOPMENT OF A PRE-PROCESSING WORKFLOW FOR LIQUID CHROMATOGRAPHY TANDEM MASS SPECTROMETRY PROTEOMICS DATA
(2022-11-15)Introduction: Omics technological advancements have improved the ability to quickly collect significant amounts of data and efficiently support scientific research. The Proteomics platform is not an exception as the large ... -
ASSESSING THE IMPACTS OF BEACH SEINES ON THE POPULATION STRUCTURE OF Leptoscarus vaigiensis QUOY AND GAIMARD, 1824 AND Siganus sutor VALENCIENNES, 1835 IN SOUTH COAST KENYA
(Pwani University, 2021-10-13)The small-scale fishery in Kenya is an important source of food and livelihood for the coastal fishing communities. The fishery is characterized by multi-species, multi-gear, open access, and poor management. This has ... -
OPTO-ELECTRICAL CHARACTERIZATION OF BIO-DYE EXTRACT FROM Adansonia digitata (BAOBAB) AND Azadirachta indica (NEEM TREE) LEAVES FOR DYE SENSITIZED SOLAR CELL APPLICATION
(Pwani University, 2022-12-13)Solar power harvesting research has been primarily focused on developing solar cells that are both affordable and environmentally friendly. Among the extensively researched technologies are Perovskite, Quantum Dot (Q.D), ... -
CHARACTERIZATION OF AFLATOXIN-PRODUCING ASPERGILLUS SPECIES IN CASHEW NUTS COLLECTED FROM THE COASTAL REGION OF KENYA
(Pwani University, 2022-12-13)Cashew trees (Anacardium occidentale) are among the main cash crops in coastal Kenya grown for their nut and apples. Cashew nuts have a high nutritional value which makes them highly susceptible to fungal growth and mold ... -
EFFECTIVENESS OF LIGHT-EMITTING DIODES IN REDUCTION OF SEA TURTLE BYCATCH IN ARTISANAL BOTTOM-SET GILLNET FISHERY IN SELECTED SITES, NORTH-COAST KENYA
(Pwani University, 2022-03-13)The artisanal gillnet fishery is found in most of the world's oceans and is responsible for a high rate of sea turtle bycatch. Between December 2016 and December 2017, this study assessed the effectiveness of light-emitting ... -
POPULATION GENETIC STRUCTURE OF THE WHITE TEATFISH, HOLOTHURIA FUSCOGILVA, IN SOUTH-COAST, KENYA
(Pwani University, 2022-02-13)The white teatfish, Holothuria fuscogilva, is widely distributed in coastal areas, around coral reefs and sea grasses in the Indo-Pacific region. In Kenya, the species is distributed in areas of shallow reefs, with higher ... -
INVESTIGATING Pf-PHISTb AS TARGET FOR NATURALLY ACQUIRED IMMUNITY AND THEIR UTILITY IN BLOCKING GAMETOCYTE TRANSMISSION
(Pwani University, 2022-09-01)Introduction: Plasmodium falciparum is a major parasite causing malaria predominantly in sub-Saharan Africa region and a leading cause of morbidity and mortality. A lot of effort has been made to understand the malaria ... -
PATTERNS, REPETITION AND VISUAL IMAGERY IN BANGO SONGS: AN ANALYSIS OF SELECTED SONGS BY JOSEPH NGALA
(Pwani University, 2022-06-01)This study investigated the patterns of composition, systems of repetition and visual imagery in five of Mzee Joseph Katana Ngala’s bango songs: “Kadzo”, “Simba”, “Adam na Hawa”, “Vituko” and “Moyo Tulia”. The objectives ... -
SCHOOL BASED FACTORS INFLUENCING ACQUISITION OF BASIC MATHEMATICS COMPETENCIES AMONG GRADE THREE PUPILS IN PUBLIC PRIMARY SCHOOLS IN MAGARINI SUB COUNTY, KILIFI COUNTY, KENYA
(Pwani University, 2022-09-01)Globally, mathematics is a key component in the scientific and technological innovations, in the social, economic, political, and geographical aspects of man. The acquisitions of basic mathematics competencies for the early ... -
INFLUENCE OF PRE-EXISTING IMMUNE ACTIVATION BY PARASITES ON SARS-CoV-2 IMMUNE RESPONSE
(Pwani University, 2022-03-01)Introduction: Despite the high burden of COVID-19 worldwide, the number of COVID-19 related cases and deaths are markedly low in Africa compared to other continents. Mechanisms explaining this occurrence deserve investigation. ... -
BIOENGINEERING OF PLASMODIUM FALCIPARUM SPECIFIC MONOCLONAL ANTIBODIES FOR ENHANCED NEUTROPHIL FUNCTION
(Pwani University, 2022-10-17)Introduction: Malaria remains a major public health concern. In the last two decades, malaria control strategies have significantly reduced the global disease burden. However, these malaria control gains have recently ... -
PARALLELIZING LONG-READ DE NOVO GENOME ASSEMBLERS ON MIXED ARCHITECTURES (CPU/GPU) WITH COMPUTE UNIFIED DEVICE ARCHITECTURE (CUDA)
(Pwani University, 2022-04-11)The computational challenge of de novo genome assembly (when no reference genome is available) is hard to tackle when millions to billions of short reads must be assembled into contigs and further into scaffolds. Current ... -
GROWTH AND DIFFERENTIATION FACTOR 15: A BIOMARKER OF DISEASE TOLERANCE IN HUMAN MALARIA INFECTION
(Pwani University, 2022-03-17)Currently, artesunate is the most effective antimalarial drug for treating severe malaria patients as it clears the parasite relatively quickly. Despite being treated with artesunate, about 15-20% of children admitted ... -
CLONING, EXPRESSION AND IMMUNOLOGICAL SCREENING OF DENGUE VIRUS ENVELOPE PROTEIN CONSTRUCTS
(Pwani University, 2022-03-17)Dengue virus (DENV) infects humans by causing mild fever and sometimes, advances to severe haemorrhagic fever characterized by capillary leakage. The mosquito vector Aedes aegypti is found predominantly in the tropical ... -
EVALUATE VIRAL HAEMORRHAGIC FEVER OUTBREAKS IN UGANDA TO DISTINGUISH CONTINUED HUMAN TO HUMAN TRANSMISSION VIA SURVIVORS FROM ZOONOTIC SPILLOVER EVENTS (2000-2019)
(Pwani University, 2021-08-26)INTRODUCTION: Uganda has experienced repeated outbreaks of viral haemorrhagic fevers (VHFs) over the last 20 years (Mbonye et al., 2012); Ebola Virus Disease (EVD) occurred in Gulu in 2000; Bundibugyo in 2007; Luweero in ... -
UNDERSTANDING THE SOURCES OF INTRODUCTIONS AND GENETIC DIVERSITY OF ROTAVIRUS A STRAINS THROUGH WHOLE GENOME ANALYSIS OF ROTAVIRUS G8P[4] AND G9P[8] STRAINS DETECTED IN KILIFI KENYA, 2010 - 2019
(Pwani University, 2021-10-08)Background: Rotavirus Group A (RVA) is the primary cause of severe dehydrating diarrhoea in young children. Notwithstanding the introduction of the RVA vaccination in several countries, RVA continues to be a major cause ... -
EFFECTS OF VITAMIN D STATUS ON PNEUMOCOCCAL VACCINE RESPONSES IN CHILDREN BELOW FIVE YEARS WITHIN KILIFI COUNTY, KENYA
(Pwani University, 2022-03-11)Background: Pneumonia is a major public health problem and a leading cause of death in children under 5 years in low and middle-income countries (LMICS). Despite vaccination, pneumonia remains a leading cause of high ...