Browsing Department of Biological Sciences by Title
Now showing items 34-53 of 57
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GENOME-WIDE ASSOCIATION STUDY OF VITAMIN D STATUS IN KENYAN CHILDREN IN KILIFI AND GAMBIAN CHILDREN IN WEST KIANG
(Pwani University, 2022-11-11)Vitamin D deficiency is a major public health issue linked to autoimmune disorders, cancer, cardiovascular and musculoskeletal diseases among other medical conditions. The link between vitamin D status and these diseases ... -
GROWTH AND DIFFERENTIATION FACTOR 15: A BIOMARKER OF DISEASE TOLERANCE IN HUMAN MALARIA INFECTION
(Pwani University, 2022-03-17)Currently, artesunate is the most effective antimalarial drug for treating severe malaria patients as it clears the parasite relatively quickly. Despite being treated with artesunate, about 15-20% of children admitted ... -
HOOK SIZE SELECTIVITY IN THE HANDLINE FISHERIES OF SHIMONI, SOUTH COAST KENYA
(Pwani Unversity, 2017-05-06)Handline fisheries employ hooks of different sizes and therefore select fish according to species and size which can influence the composition of fish stocks in any given fishery. The aim of this study was to assess the ... -
IMMUNOGLOBULIN ANNOTATION OPTIMIZING AND BENCHMARKING; NOVEL GERMLINE ALLELE DISCOVERY IN SELECTED AFRICAN BOVINE BREEDS
(Pwani University, 2021-03-2)Antibodies are critical molecules of the adaptive immune response of vertebrates. For an animal to neutralize the pathogens it will encounter in its lifetime, the diversity of antibodies it will need to produce is enormous. ... -
IMPACT OF INITIAL HANDLING ON QUALITY AND SHELF LIFE OF PENAEID SHRIMPS BY ARTISANAL FISHERMEN IN KURAWA NORTH COAST KENYA
(Pwani University, 2017-07)The present study was conducted to determine the effect of initial handling of shrimps after they were caught by the small scale fisheries of Kurawa North coast Kenya. Further, the study was aimed at assessing the effect ... -
INFLUENCE OF PRE-EXISTING IMMUNE ACTIVATION BY PARASITES ON SARS-CoV-2 IMMUNE RESPONSE
(Pwani University, 2022-03-01)Introduction: Despite the high burden of COVID-19 worldwide, the number of COVID-19 related cases and deaths are markedly low in Africa compared to other continents. Mechanisms explaining this occurrence deserve investigation. ... -
INVESTIGATING Pf-PHISTb AS TARGET FOR NATURALLY ACQUIRED IMMUNITY AND THEIR UTILITY IN BLOCKING GAMETOCYTE TRANSMISSION
(Pwani University, 2022-09-01)Introduction: Plasmodium falciparum is a major parasite causing malaria predominantly in sub-Saharan Africa region and a leading cause of morbidity and mortality. A lot of effort has been made to understand the malaria ... -
INVESTIGATING THE ROLE OF SOLUBLE IMMUNE CHECKPOINT MARKERS IN INFLAMMATORY DISEASES
(PWANI UNIVERSITY, 2023-05-24)Introduction: Membrane-bound immune checkpoint markers (mICMs) are inhibitory and activatory receptors and ligands expressed on immune cells and are associated with immune regulation. Studies have reported the association ... -
KINETICS OF RTS, S/AS01-INDUCED ANTI-CSP ANTIBODIES IN YOUNG KENYAN CHILDREN
(Pwani University, 2021-05-23)RTS,S/AS01, the leading malaria vaccine, is currently under a pilot study with the aim of introducing it in routine immunization of children. Though there are no well-established correlates of protection, specific anti-CSP ... -
METATRANSCRIPTOMICS ANALYSIS OF CORAL MUCUS-ASSOCIATED MICROBIOME IN THE KENYAN COAST
(Pwani University, 2022-12-16)Coral reefs are significant marine ecosystems located in shallow tropical and subtropical seas that provide important services. More than 25% of all marine species depend on coral reefs as breeding and feeding sites, as ... -
OPTO-ELECTRICAL CHARACTERIZATION OF BIO-DYE EXTRACT FROM Adansonia digitata (BAOBAB) AND Azadirachta indica (NEEM TREE) LEAVES FOR DYE SENSITIZED SOLAR CELL APPLICATION
(Pwani University, 2022-12-13)Solar power harvesting research has been primarily focused on developing solar cells that are both affordable and environmentally friendly. Among the extensively researched technologies are Perovskite, Quantum Dot (Q.D), ... -
PARALLELIZING LONG-READ DE NOVO GENOME ASSEMBLERS ON MIXED ARCHITECTURES (CPU/GPU) WITH COMPUTE UNIFIED DEVICE ARCHITECTURE (CUDA)
(Pwani University, 2022-04-11)The computational challenge of de novo genome assembly (when no reference genome is available) is hard to tackle when millions to billions of short reads must be assembled into contigs and further into scaffolds. Current ... -
PATTERNS, REPETITION AND VISUAL IMAGERY IN BANGO SONGS: AN ANALYSIS OF SELECTED SONGS BY JOSEPH NGALA
(Pwani University, 2022-06-01)This study investigated the patterns of composition, systems of repetition and visual imagery in five of Mzee Joseph Katana Ngala’s bango songs: “Kadzo”, “Simba”, “Adam na Hawa”, “Vituko” and “Moyo Tulia”. The objectives ... -
PHYLOGENETIC EVOLUTION AND GEOGRAPHIC TRANSMISSION PATTERNS OF THE RICE BLAST PATHOGEN MAGNAPORTHE ORYZAE IN AFRICA
(Pwani University, 2020-01-23)Rice blast disease, caused by the fungal pathogen Magnaporthe oryzae, is the most disastrous disease in rice, and adversely constrains the growth and productivity of the crop worldwide. Outbreaks of the disease reoccur in ... -
POPULATION GENETIC STRUCTURE OF THE WHITE TEATFISH, HOLOTHURIA FUSCOGILVA, IN SOUTH-COAST, KENYA
(Pwani University, 2022-02-13)The white teatfish, Holothuria fuscogilva, is widely distributed in coastal areas, around coral reefs and sea grasses in the Indo-Pacific region. In Kenya, the species is distributed in areas of shallow reefs, with higher ... -
PREDICTION OF ALTERNATIVE SPLICING EVENTS ON PANTRANSCRIPTS
(2024-06-24)Alternative Splicing (AS) is a regulation mechanism that contributes to protein diversity and is also associated to many diseases and tumors. Alternative splicing events quantification from RNA-Seq reads is a crucial ... -
QUANTIFYING ALLO-COPROPHAGY IN LABORATORY RATS FROM DEEP SHOTGUN SEQUENCING DATA OF THE GUT
(PWANI UNIVERSITY, 2023-10-24)Commensal microorganisms can be transferred between humans who come in contact and/or who share a living space. The transmission of these commensal microorganisms could have important health consequences. It is therefore ... -
REPRODUCTIVE BIOLOGY OF EXPLOITED POPULATIONS OF THE EMPEROR ANGELFISH, Pomacanthus imperator BLOCH, 1787 ALONG THE KENYAN COAST
(Pwani Unversity, 2016-05-05)Substantial proportion of the Pomacanthus imperator are traded in terms of value and quantity and also harvested as food in the artisanal fishery in Kenya. However information on their reproductive biology is scanty. In ... -
ROLE OF ENTOMOLOGICAL FACTORS IN SUSTENANCE OF RESIDUAL MALARIA PARASITE TRANSMISSION IN KILIFI COUNTY, KENYAN COAST
(Pwani Unversity, 2018-03-08)Malaria vector control strategies have been rolled out in malaria endemic areas leading to reduction in disease transmission and morbidity in some regions. However, the persistence in local malaria transmission has not ... -
SCHOOL BASED FACTORS INFLUENCING ACQUISITION OF BASIC MATHEMATICS COMPETENCIES AMONG GRADE THREE PUPILS IN PUBLIC PRIMARY SCHOOLS IN MAGARINI SUB COUNTY, KILIFI COUNTY, KENYA
(Pwani University, 2022-09-01)Globally, mathematics is a key component in the scientific and technological innovations, in the social, economic, political, and geographical aspects of man. The acquisitions of basic mathematics competencies for the early ...