Browsing Department of Biochemistry and Biotechnology by Title
Now showing items 1-12 of 12
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CLONING AND CHARACTERIZATION OF PWL1 AND PWL2 HOST-SPECIES SPECIFICITY GENES OF THE FINGER MILLET BLAST PATHOGEN, MAGNAPORTHE ORYZAE
(Pwani University, 2020-12-02)Blast disease, caused by the filamentous ascomycete fungus, Magnaporthe oryzae, is the most devastating disease affecting finger millet (Eleusine coracana subsp. coracana) production in eastern Africa. The fungus also ... -
ELUCIDATING HUMAN RHINOVIRUS TRANSMISSION PATHWAYS AT DIFFERING SCALES OF SOCIAL ORGANISATION USING SEQUENCE DATA
(Pwani University, 2021-01-05)Background: Human rhinovirus (HRV) is a common viral agent associated with high diversity and a broad spectrum of respiratory disease. Its epidemiological understanding is currently restricted to observations on the ... -
ESTABLISHING THE GENETIC BASIS FOR RESISTANCE AND VIRULENCE IN FINGER MILLET - Magnaporthe oryzae INTERACTIONS USING GENOME-WIDE ASSOCIATION STUDIES IN EASTERN AFRICA
(Pwani University, 2021-03-09)Finger millet (Eleusine coracana spp. coracana) is an important food and income source for millions of smallholder farmers in eastern Africa. Most of the farmers use unimproved varieties which are vulnerable to biotic and ... -
EVALUATING THE ACCURACY OF GENOTYPE IMPUTATION IN THE MAJOR HISTOCOMPATIBILITY COMPLEX REGION IN SELECTED AFRICAN POPULATIONS
(Pwani University, 2022-03-9)Genome wide association studies (GWAS) typically use genotyping arrays to genotype large sets of individuals and thus determine which SNPs are significantly overrepresented in the cases compared to the controls and in this ... -
EVALUATING THE EFFECTS OF BIOLOGICAL AND EXPERIMENTAL FACTORS ON THE COMPOSITION OF THE GUT MICROBIOME TAXONOMIC PROFILES AT SPECIES LEVEL IN LABORATORY RATS
(PWANI UNIVERSITY, 2023-12-24)Co-evolutionary association between mammals and their microbiota is considered vital through influencing physiology, behavior, as well as their general health. The gut microbiota affects a variety of characteristics ... -
FUNGAL DIVERSITY IN THE PHYLLOSPHERE OF CASHEW (ANACARDIUM OCCIDENTALE) FROM COASTAL KENYA
(PWANI UNIVERSITY, 2023-09-24)Cashew trees (Anacardium occidentale) grown within coastal Kenya are a key cash crop with associated economic and nutritional values from nuts and apples. Cashew ecosystems host diverse fungal communities as epiphytes ... -
GENOME-WIDE ASSOCIATION STUDY FOR AGRO-MORPHOLOGICAL TRAITS AND PIPELINE DEVELOPMENT TO ASSESS POPULATION STRUCTURE IN FINGER MILLET
(Pwani University, 2022-11-03)Finger millet is a small-grained millet that is ranked as the third most important after pearl millet and foxtail millet. There are diverse finger millet varieties that are grown in eastern Africa characterized by diverse ... -
GENOMIC AND SUB-GENOMIC CHARACTERIZATION OF SARS-COV-2 SAMPLES IN KENYA
(Pwani University, 2022-02-03)Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the etiological agent of Corona Virus Disease 2019 (COVID-19), has spread rapidly across the human population, resulting in up to 213 million confirmed cases ... -
METABOLOMIC ANALYSIS OF TRYPANOSOMA CONGOLENSE AND LEISHMANIA MEXICANA TREATED WITH SELECTED ANTIPARASITIC DRUGS AND IN SILICO MODELLING OF POTENTIAL DRUG TARGETS
(Pwani University, 2022-12)Animal African Trypanosomiasis (AAT) is a devastating parasitic disease caused by a variety of haemoflagellate extracellular protozoa of the genus Trypanosoma. It is endemic in 37 of the 55 countries in Africa and is ... -
DE NOVO GENOME ASSEMBLY AND ANNOTATION OF CHEMOSENSORY GENES IN HIPPOBOSCA CAMELINA AND HIPPOBOSCA VARIEGATA
(PWANI UNIVERSITY, 2024-05-24)Hippoboscids (keds or flies) are obligate hematophagous or blood-sucking ectoparasites that infest birds, mammals, and incidentally humans. They transmit pathogens such as Anaplasma camelii transmitted by Hippobosca ... -
POPULATION STRUCTURE AND GENETIC DIVERSITY ASSESSMENT OF EASTERN AFRICA FINGER MILLET BLAST FUNGUS USING GENOME-WIDE SNPS
(Pwani University, 2020-09-23)Finger millet (Eleusine coracana) is a key staple crop in eastern Africa cultivated mainly by smallholder farmers. It can withstand high temperatures, salinity, drought stress and low soil fertility. The use of unimproved ... -
WHOLE GENOME CHARACTERIZATION OF ROTAVIRUS GROUP A G1P[8] STRAINS IN KILIFI, KENYA, BEFORE AND AFTER VACCINE INTRODUCTION
(Pwani University, 2022-04-05)Group A rotaviruses (RVA) are a leading cause of severe acute gastroenteritis in young children worldwide. Kenya introduced the monovalent Rotarix® vaccine (derived from a live attenuated G1P[8] rotavirus strain) in ...