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dc.contributor.authorTimothy J Donohoe
dc.contributor.authorPaul M Guyo
dc.contributor.authorRakesh R Harji
dc.contributor.authorMadeleine Helliwell
dc.date.accessioned2012-10-23T11:14:42Z
dc.date.available2012-10-23T11:14:42Z
dc.date.issued1998-05-07
dc.identifier.citation. Volume 39, Issue 19, 7 May 1998, Pages 3075–3078en_US
dc.identifier.urihttp://hdl.handle.net/123456789/332
dc.descriptionThe original publication is available at http://www.sciencedirect.com/science/article/pii/S0040403998003621en_US
dc.description.abstractThe Birchreduction of electron-deficient 3-substituted pyrroles is described. Use of a reductive alkylation procedure involving sodium metal in liquid ammonia gave good yields of 4-alkyl-2-pyrrolines. The identity of these products was proven by an X-ray structure of a crystalline derivative. Moreover, the pyrroles used in this study could be readily prepared by reaction of TOSMIC with acrylic amides and esters and, once the reduction was complete, the ester activating group could be easily removed to yield the corresponding N-protected β-proline derivatives.en_US
dc.description.sponsorshipPwani Universityen_US
dc.language.isoenen_US
dc.publisherELSELVIERen_US
dc.subjectBirchen_US
dc.subjectpyrrolesen_US
dc.subjectreductionen_US
dc.titleThe Birchreduction of 3-substituted pyrrolesen_US
dc.typeArticleen_US


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