Show simple item record

dc.contributor.authorTimothy J. Donohoe
dc.contributor.authorPaul M. Guyo
dc.contributor.authorMadeleine Helliwell
dc.date.accessioned2012-10-23T14:35:01Z
dc.date.available2012-10-23T14:35:01Z
dc.date.issued1999-01-15
dc.identifier.citationVolume 40, Issue 3, 15 January 1999, Pages 435–438en_US
dc.identifier.urihttp://hdl.handle.net/123456789/334
dc.descriptionThe original publication is available at http://www.sciencedirect.com/science/article/pii/S0040403998023958en_US
dc.description.abstractThe Birchreduction has been applied to electron-deficient pyrroles substituted with a chiral auxiliary at the C-2 position. Using either 8-phenylmenthol ortrans-2-(α-cumyl)cyclohexanol (TCC) as auxiliaries, high levels of stereoselectivity were obtained. Moreover, the auxiliary could be removed using a high-yielding three-step sequence to furnish substituted dehydroproline derivatives with high enantiomeric purity. By choosing either (−)-8-phenylmenthol or (+)-TCC as an auxiliary either enantiomer of the dehydroproline product could be obtained.en_US
dc.description.sponsorshipPwani Universityen_US
dc.language.isoenen_US
dc.publisherELSELVIERen_US
dc.subjectstereoselectiveen_US
dc.subjectpyrrolesen_US
dc.subjectBirchen_US
dc.titleThe stereoselectiveBirchreduction of pyrrolesen_US
dc.typeArticleen_US


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record